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Literature summary for 2.3.1.150 extracted from

  • Allen, R.S.; Miller, J.A.; Chitty, J.A.; Fist, A.J.; Gerlach, W.L.; Larkin, P.J.
    Metabolic engineering of morphinan alkaloids by over-expression and RNAi suppression of salutaridinol 7-O-acetyltransferase in opium poppy (2008), Plant Biotechnol. J., 6, 22-30.
    View publication on PubMed

Application

Application Comment Organism
biotechnology increases in pharmaceutical alkaloid content of potential economic significance have been achieved, RNAi suppression is a powerful way to obtain products that poppy does not normally accumulate Papaver somniferum

Cloned(Commentary)

Cloned (Comment) Organism
Agrobacterium-mediated transfection of Papaver somniferum with the salutaridinol 7-O-acetyltransferase gene, 21 transgenic opium poppy plants over-expressing SalAT are analysed in three separate glasshouse trials, suppression of SalAT by RNAi, SalAT involved in alkaloid accumulation Papaver somniferum

Organism

Organism UniProt Comment Textmining
Papaver somniferum
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opium poppy plants, 21 transgenic SalAT over-expression lines are produced
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Source Tissue

Source Tissue Comment Organism Textmining
fruit capsule
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Papaver somniferum
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seed
-
Papaver somniferum
-
stem
-
Papaver somniferum
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
salutaridinol + acetyl-CoA morphinan pathway Papaver somniferum salutaridinol-7-O-acetate + CoA
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Synonyms

Synonyms Comment Organism
SalAT
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Papaver somniferum
salutaridinol 7-O-acetyltransferase
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Papaver somniferum