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Literature summary for 2.3.1.15 extracted from

  • Cattaneo, E.R.; Pellon-Maison, M.; Rabassa, M.E.; Lacunza, E.; Coleman, R.A.; Gonzalez-Baro, M.R.
    Glycerol-3-phosphate acyltransferase-2 is expressed in spermatic germ cells and incorporates arachidonic acid into triacylglycerols (2012), PLoS ONE, 7, e42986.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.15

Cloned(Commentary)

Cloned (Comment) Organism
expression in CHO-K1 cell Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus D3ZI76
-
-

Source Tissue

Source Tissue Comment Organism Textmining
spermatocyte
-
 Rattus norvegicus
-
testis expression only in primary spermatocytes. During rat sexual maturation, both the testicular TAG content and the arachidonic acid content in the triacylglycerol fraction peak at 30 days, matching the highest expression of Gpat2 mRNA and protein Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-arachidonoyl-sn-glycerol 3-phosphate
-
 ?
docosahexaenoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-docosahexaenoyl-sn-glycerol 3-phosphate
-
 ?
eicosapentaenoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-eicosapentaenoyl-sn-glycerol 3-phosphate
-
 ?
linoleoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-linoleoyl-sn-glycerol 3-phosphate
-
 ?
oleoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
GPAT2
-
 Rattus norvegicus

General Information

General Information Comment Organism
physiological function isoform GPAT2 overexpression in CHO-K1 cells increased arachidonoyl-CoA esterification and accumulation of triacylglycerols. GPAT2 expression is linked to arachidonoyl-CoA incorporation into triacylglycerols in spermatogenic germ cells Rattus norvegicus