Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | subcellular localization of Gat1p and Gat2p are compared using fluorescence microscopy and subcellular fractionation using equilibrium density gradients. Gat1p and Gat2p overlap mostly in their localization and are microsomal GPATs, localized to both perinuclear and cortical endoplasmic reticula in actively proliferating cells | Saccharomyces cerevisiae | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
possesses two GPAT | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | - |
Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
GAT1p | - |
Saccharomyces cerevisiae |
GAT2p | - |
Saccharomyces cerevisiae |
glycerol-3-phosphate acyltransferase 1 | - |
Saccharomyces cerevisiae |
GPAT | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
malfunction | loss of function of Gat1p and Gat2p is masked by the compensatory effect of their redundant partner. The complete lack of GPAT results in cell death, with multibudded cells containing divided nuclei | Saccharomyces cerevisiae |
physiological function | overexpression Gat1p in the absence of endogenous GPATs results in elongated cells with a normal cortical edoplasmic reticulum positioned underneath the plasma membrane, while excess Gat2p results in larger and round cells with an irregular layout of membranes, with pronounced invaginations also affecting the plasma membrane morphology | Saccharomyces cerevisiae |