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Literature summary for 2.3.1.15 extracted from
- sn-Glycerol-3-phosphate acyltransferase from Escherichia coli (1997), Biochim. Biophys. Acta, 1348, 3-9.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ATP | activation of acyltransferase in isolated membrane preparations | Escherichia coli |  |
| Phospholipids | absolutely required | Escherichia coli | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| phosphate | - |
Escherichia coli | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0046 | - |
palmitoyl-CoA | - |
Escherichia coli | |
| 0.12 | - |
glycerol 3-phosphate | - |
Escherichia coli | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrial inner membrane | cytoplasmic side of inner membrane | Escherichia coli | 5743 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-[acyl-carrier protein] + sn-glycerol 3-phosphate | Escherichia coli | acyl-[acyl-carrier-protein] is probably the physiological substrate | acyl-carrier protein + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Renatured (Commentary)
| Renatured (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + sn-glycerol 3-phosphate | preference for saturated fatty acyl-CoAs | Escherichia coli | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
| acyl-[acyl-carrier protein] + sn-glycerol 3-phosphate | acyl-[acyl-carrier-protein] is probably the physiological substrate | Escherichia coli | acyl-carrier protein + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
| palmitoyl-CoA + sn-glycerol 3-phosphate | - |
Escherichia coli | CoA + 1-palmitoyl-sn-glycerol 3-phosphate | - |
? | |
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