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Literature summary for 2.3.1.147 extracted from
- The activities of monocyte lysophosphatidylcholine acyltransferase and coenzyme A-independent transacylase are changed by the inflammatory cytokines tumor necrosis factor alpha and interferon gamma (2005), Biochim. Biophys. Acta, 1733, 232-238.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| interferon gamma | i.e. IFN-gamma, human, recombinant, increases enzyme activity in microsomes by about 100% | Homo sapiens | |
| Tumor necrosis factor alpha | i.e. TNF-alpha, human, recombinant, 50% increase in enzyme activity within 30 min incubation of microsomes | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Homo sapiens | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| MM6 cell | i.e. mono-mac 6, monocytic cell line | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-alkyl-2-lyso-glyceryl phosphorylcholine + oleoyl-CoA | - |
Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CoAIT | - |
Homo sapiens |
| Coenzyme A-independent transacylase | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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