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Literature summary for 2.3.1.147 extracted from

  • Winkler, J.D.; Eris, T.; Sung, C.M.; Chabot-Fletcher, M.; Mayer, R.J.; Surette, M.E.; Chilton, F.H.
    Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells (1996), J. Pharmacol. Exp. Ther., 279, 956-966.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine
-
 Homo sapiens
1-[2-[3-(4-Chloro-3-trifluoromethylphenyl)ureido]-4-trifluoromethyl phenoxy]-4,5-dichlorobenzene sulfonic acid i.e. SK&F 45905 Homo sapiens
Diethyl 7-(1,4,5-triphenyl imidazol-2-yloxy)heptane phosphonate SK&F 98628 Homo sapiens
Diethyl 7-(3,4,5-triphenyl-2-oxo-2,3-dihydro-imidazol-1-yl)heptane-phosphonate i.e. SK&F 98625 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens inhibition of the enzyme can be linked to blockade of proliferation and the induction of apoptosis in HL-60 cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
monocyte HL-60 monocytic leukemia cells Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information inhibition of the enzyme can be linked to blockade of proliferation and the induction of apoptosis in HL-60 cells Homo sapiens ?
-
 ?