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Literature summary for 2.3.1.146 extracted from

  • Seppanen, S.K.; Syrjala, L.; von Weissenberg, K.; Teeri, T.H.; Paajanen, L.; Pappinen, A.
    Antifungal activity of stilbenes in in vitro bioassays and in transgenic Populus expressing a gene encoding pinosylvin synthase (2004), Plant Cell Rep., 22, 584-593.
    View publication on PubMed

Application

Application Comment Organism
agriculture even though pinosylvin, due to its high antifungal activity, could offer new possibilities in engineering disease resistance, its synthesis in heterologous plants may be restricted by factors related to 4-coumarate:CoA ligase-substrate specificity, or metabolic channelling. Cotransformation of pinosylvin-forming stilbene synthase and cinnamate-specific 4-coumarate:CoA ligase could offer a feasible tool to avoid these restrictions Pinus sylvestris

Cloned(Commentary)

Cloned (Comment) Organism
pinosylvin-synthase-encoding gene from Pinus sylvestris is transferred into aspen (Populus tremula) and two hybrid aspen clones (Populus tremula tremuloides) by Agrobacterium tumefaciens mediated transformation. Transgenic plants accumulated pinosylvin synthase-specific mRNA and showed stilbene synthase enzyme activity in vitro. Transgenic aspen line H4 showed increased resistance to Phellinus tremulae, while two hybrid aspen transformants decayed faster than the control trees. No accumulation of stilbenes in the transgenic plantlets Pinus sylvestris

Organism

Organism UniProt Comment Textmining
Pinus sylvestris
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