Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.144 extracted from

  • Eudes, A.; Teixeira Benites, V.; Wang, G.; Baidoo, E.E.; Lee, T.S.; Keasling, J.D.; Loque, D.
    Precursor-directed combinatorial biosynthesis of cinnamoyl, dihydrocinnamoyl, and benzoyl anthranilates in Saccharomyces cerevisiae (2015), PLoS ONE, 10, e0138972.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
synthesis by exploiting the substrate flexibility of both 4-coumaroyl:CoA ligase 4CL5 from Arabidopsis thaliana and HCBT, rapid biosynthesis of more than 160 cinnamoyl, dihydrocinnamoyl, and benzoyl anthranilates in yeast can be achieved upon feeding with both natural and non-natural cinnamates, dihydrocinnamates, benzoates, and anthranilates Dianthus caryophyllus

Organism

Organism UniProt Comment Textmining
Dianthus caryophyllus O24645 isoform HCBT1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information by exploiting the substrate flexibility of both 4-coumaroyl:CoA ligase 4CL5 from Arabidopsis thaliana and HCBT, rapid biosynthesis of more than 160 cinnamoyl, dihydrocinnamoyl, and benzoyl anthranilates in yeast can be achieved. The enzyme offers flexibility for a wide range of acyl-CoA donors, its affinity towards acceptors seems limited to anthranilates Dianthus caryophyllus ?
-
?