Crystallization (Comment) | Organism |
---|---|
2.2 A crystal structure of HRAS-like tumor suppressor 3 /LRAT chimeric enzyme in a thioester catalytic intermediate state reveals a major structural rearrangement accompanied by 3D-domain swapping dimerization not observed in native HRASLS proteins. Structural changes affecting the active site environment contribute to slower hydrolysis of the catalytic intermediate supporting efficient acyl transfer | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of chimeric proteins between LRAT and human HRASLS2, HRASLS3 and HRASLS4 by by replacing the native sequence of HRASLS2, 3, and 4 (residues 39-57) with the 30 aa mouse LRAT sequence 76DILLALTNDKERTQKVVSNKRLLLGVICKV106 | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9JI60 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
LRAT | - |
Mus musculus |