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Literature summary for 2.3.1.12 extracted from
- Hybrid pyruvate dehydrogenase complexes reconstituted from components of the complexes from Escherichia coli and Azotobacter vinelandii (1985), Eur. J. Biochem., 152, 35-41.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dihydrolipoamide + acetyl-CoA | Escherichia coli | - |
S-acetyldihydrolipoamide + CoA | - |
? |  |
| dihydrolipoamide + acetyl-CoA | Azotobacter vinelandii | - |
S-acetyldihydrolipoamide + CoA | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Azotobacter vinelandii | - |
- |
- |
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Renatured (Commentary)
| Renatured (Comment) | Organism |
|---|---|
| reconstitution with components from Escherichia coli and Azotobacter vinelandii, optimum catalytic stoichiometry of E1:E2:E3 is 1:1:0.5 | Azotobacter vinelandii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dihydrolipoamide + acetyl-CoA | - |
Escherichia coli | S-acetyldihydrolipoamide + CoA | - |
? | |
| dihydrolipoamide + acetyl-CoA | - |
Azotobacter vinelandii | S-acetyldihydrolipoamide + CoA | - |
? | |
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Release 2023.1 (January 2023)
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