Inhibitors | Comment | Organism | Structure |
---|---|---|---|
arginine | feed back inhibition, 0.16 mM, 50% inhibition; L-arginine | Neurospora crassa | |
coenzyme A | 1 mM, 30% inhibition | Neurospora crassa | |
oxaloacetate | 1 mM, 68% inhibition | Neurospora crassa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.6 | - |
glutamate | - |
Neurospora crassa | |
6.3 | - |
acetyl-CoA | - |
Neurospora crassa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + L-glutamate | Neurospora crassa | indispensible enzyme of arginine biosynthesis | CoA + N-acetyl-L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Neurospora crassa | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + L-glutamate | - |
Neurospora crassa | CoA + N-acetyl-L-glutamate | - |
? | |
acetyl-CoA + L-glutamate | indispensible enzyme of arginine biosynthesis | Neurospora crassa | CoA + N-acetyl-L-glutamate | - |
? | |
propionyl-CoA + L-glutamate | 18% of activity with acetyl-CoA | Neurospora crassa | CoA + N-propionyl-L-glutamate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.8 | 9 | - |
Neurospora crassa |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
8 | 9.5 | 38% of maximal activity at pH 8.0., 25% of maximal activity at pH 9.5 | Neurospora crassa |