Any feedback?
Literature summary for 2.2.1.6 extracted from
- Arabidopsis acetohydroxyacid synthase expressed in Escherichia coli is insensitive to the feedback inhibitors (1992), Plant Physiol., 99, 812-815.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cloned into the bacterial expression plasmid pKK233-2, expression in AHAS-deficient Escherichia coli strain MF2000 | Arabidopsis thaliana |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| chlorsulphuron | inhibition of the enzyme from Arabidopsis thaliana and of the enzyme expressed in E. coli | Arabidopsis thaliana |  |
| Leu | inhibition of the enzyme from Arabidopsis thaliana, no inhibition of the enzyme expressed in E. coli | Arabidopsis thaliana | |
| Val | inhibition of the enzyme from Arabidopsis thaliana, no inhibition of the enzyme expressed in E. coli | Arabidopsis thaliana | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate | Arabidopsis thaliana | first enzyme unique to biosynthesis of the branched chain amino acids Val, Leu, and Ile | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate | - |
Arabidopsis thaliana | 2-acetolactate + CO2 | - |
? | |
| pyruvate | first enzyme unique to biosynthesis of the branched chain amino acids Val, Leu, and Ile | Arabidopsis thaliana | ? | - |
? | |
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Release 2023.1 (January 2023)
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