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Literature summary for 2.2.1.6 extracted from

  • Chin, N.W.; Trela, J.M.
    Comparison of acetohydroxy-acid synthetases from two extreme thermophilic bacteria (1973), J. Bacteriol., 114, 674-678.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.2.1.6

Inhibitors

Inhibitors Comment Organism Structure
Ile
-
 Bacillus sp. (in: Bacteria)
Ile
-
 Thermus aquaticus
Leu no inhibition Bacillus sp. (in: Bacteria)
Leu no inhibition Thermus aquaticus
Val competitive; feed-back inhibition Bacillus sp. (in: Bacteria)
Val feed-back inhibition; noncompetitive Thermus aquaticus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Thermus aquaticus
Mg2+ required Bacillus sp. (in: Bacteria)

Organism

Organism UniProt Comment Textmining
Bacillus sp. (in: Bacteria)
-
-
-
Thermus aquaticus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate
-
 Thermus aquaticus 2-acetolactate + CO2
-
 ?
pyruvate
-
 Bacillus sp. (in: Bacteria) 2-acetolactate + CO2
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
70
-
-
 Thermus aquaticus
75
-
-
 Bacillus sp. (in: Bacteria)

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
additional information
-
-
 Thermus aquaticus
additional information
-
-
 Bacillus sp. (in: Bacteria)

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
-
 Bacillus sp. (in: Bacteria)
8
-
-
 Thermus aquaticus

Cofactor

Cofactor Comment Organism Structure
FAD required Thermus aquaticus
FAD no requirement Bacillus sp. (in: Bacteria)
thiamine diphosphate required as cofactor Thermus aquaticus
thiamine diphosphate required as cofactor Bacillus sp. (in: Bacteria)