Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cystamine | - |
Streptomyces bikiniensis | |
cystamine | - |
Streptomyces hygroscopicus | |
cystine | - |
Streptomyces bikiniensis | |
cystine | - |
Streptomyces hygroscopicus | |
formamidine disulfidedihydrochloride | - |
Streptomyces bikiniensis | |
formamidine disulfidedihydrochloride | - |
Streptomyces hygroscopicus | |
ornithine | product inhibition, most potent competitive inhibitor | Streptomyces bikiniensis | |
ornithine | product inhibition, most potent competitive inhibitor | Streptomyces hygroscopicus | |
p-chloromercuribenzoate | - |
Streptomyces bikiniensis | |
p-chloromercuribenzoate | - |
Streptomyces hygroscopicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | Streptomyces griseocarneus | - |
L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | Streptomyces galbus | - |
L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | Streptomyces humidus | - |
L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | Streptomyces ornatus | - |
L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | Streptomyces bikiniensis | biosynthesis of streptomycin | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | Streptomyces hygroscopicus | biosynthesis of streptomycin | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces bikiniensis | - |
ATCC 11062 | - |
Streptomyces galbus | - |
ATCC 14077 | - |
Streptomyces griseocarneus | - |
ATCC 12628 | - |
Streptomyces humidus | - |
ATCC 12760 | - |
Streptomyces hygroscopicus | - |
forma glebosus, ATCC 14607 | - |
Streptomyces ornatus | - |
ATCC 23265 | - |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces bikiniensis |
- |
Streptomyces hygroscopicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mycelium | - |
Streptomyces bikiniensis | - |
mycelium | - |
Streptomyces hygroscopicus | - |
mycelium | - |
Streptomyces griseocarneus | - |
mycelium | - |
Streptomyces galbus | - |
mycelium | - |
Streptomyces humidus | - |
mycelium | - |
Streptomyces ornatus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.17 | - |
- |
Streptomyces bikiniensis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arginine + 1,4-diaminobutylphosphonic acid | - |
Streptomyces bikiniensis | ornithine + ? | - |
? | |
arginine + 2-amino-2-deoxy-neoinositol 5-phosphate | - |
Streptomyces bikiniensis | ornithine + ? | - |
? | |
arginine + 2-amino-2-deoxy-neoinositol 5-phosphate | - |
Streptomyces hygroscopicus | ornithine + ? | - |
? | |
arginine + 2-deoxystreptamine 6-phosphate | - |
Streptomyces bikiniensis | N-amidino-2-deoxystreptamine 6-phosphate + ornithine | - |
? | |
arginine + 2-deoxystreptamine 6-phosphate | - |
Streptomyces hygroscopicus | N-amidino-2-deoxystreptamine 6-phosphate + ornithine | - |
? | |
arginine + 2-deoxystreptidine | - |
Streptomyces bikiniensis | ornithine + ? | - |
? | |
arginine + 2-deoxystreptidine | - |
Streptomyces hygroscopicus | ornithine + ? | - |
? | |
arginine + scyllo-inosamine 4-phosphate | - |
Streptomyces bikiniensis | ornithine + N-amidino-scyllo-inosamine-4-phosphate | - |
? | |
arginine + scyllo-inosamine 4-phosphate | - |
Streptomyces hygroscopicus | ornithine + N-amidino-scyllo-inosamine-4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | - |
Streptomyces griseocarneus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | - |
Streptomyces galbus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | - |
Streptomyces humidus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | - |
Streptomyces ornatus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | biosynthesis of streptomycin | Streptomyces bikiniensis | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate | biosynthesis of streptomycin | Streptomyces hygroscopicus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate | - |
Streptomyces bikiniensis | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate | - |
Streptomyces hygroscopicus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate | - |
Streptomyces griseocarneus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate | - |
Streptomyces galbus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate | - |
Streptomyces humidus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate | - |
Streptomyces ornatus | L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate | - |
? | |
L-canavanine + L-ornithine | - |
Streptomyces bikiniensis | L-canaline + L-arginine | - |
r | |
L-canavanine + L-ornithine | - |
Streptomyces hygroscopicus | L-canaline + L-arginine | - |
r | |
additional information | inosamine derivatives must be phosphorylated to serve as substrates, phosphates must be esterified with the hydroxyl group para to the amino group to be transamidinated | Streptomyces bikiniensis | ? | - |
? | |
streptidine phosphate + glycylglycine | - |
Streptomyces bikiniensis | ? | - |
? | |
streptidine phosphate + glycylglycine | - |
Streptomyces griseocarneus | ? | - |
? |