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Literature summary for 2.1.3.3 extracted from

  • Pierson, D.L.; Cox, S.L.; Gilbert, B.E.
    Human ornithine transcarbamylase. Purification and characterization of the enzyme from normal liver and the liver of a Reyes syndrome patient (1977), J. Biol. Chem., 252, 6464-6469.
    View publication on PubMed
Search for more literature for 2.1.3.3

Inhibitors

Inhibitors Comment Organism Structure
L-2,4-diaminobutyric acid
-
 Homo sapiens
L-2-Amino-4-pentenoic acid
-
 Homo sapiens
L-2-aminobutyrate L-isomer Homo sapiens
L-leucine
-
 Homo sapiens
L-norvaline
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36500
-
 3 * 36500, SDS-PAGE Homo sapiens
110000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 normal liver enzyme and enzyme from a liver of a patient with Reye's syndrome
-

Purification (Commentary)

Purification (Comment) Organism
enzyme from normal liver and liver of a Reye's syndrome patient, DEAE-cellulose, hydroxylapatite, Sephadex G-200 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
83.3
-
 enzyme from a liver of a Reye's syndrome patient Homo sapiens
86.5
-
 enzyme from normal liver Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
carbamoyl phosphate + L-ornithine
-
 Homo sapiens phosphate + L-citrulline
-
 ?

Subunits

Subunits Comment Organism
trimer 3 * 36500, SDS-PAGE Homo sapiens