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Literature summary for 2.1.2.5 extracted from
- Localization of Golgi 58K protein (formiminotransferase cyclodeaminase) to the centrosome (2006), Histochem. Cell Biol., 126, 251-259.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| centrosome | more abundantly around the mother centriole. The centrosome localization of FTCD continues throughout the cell cycle and is not disrupted after Golgi fragmentation, which is induced by colcemid and brefeldin A. FTCD in the centrosome may be associated with polyglutamylated residues of centriole microtubules and may play a role in providing centrioles with glutamate produced by cyclodeaminase domains of FTCD | Homo sapiens | 5813 | - |
| Golgi apparatus | - |
Homo sapiens | 5794 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| tetrahydrofolate + N-formimidoyl-L-glutamate | Homo sapiens | FTCD in the centrosome may be associated with polyglutamylated residues of centriole microtubules and may play a role in providing centrioles with glutamate produced by cyclodeaminase domains of FTCD | 5-formimidoyltetrahydrofolate + L-glutamate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O05954 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| oviduct | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| tetrahydrofolate + N-formimidoyl-L-glutamate | - |
Homo sapiens | 5-formimidoyltetrahydrofolate + L-glutamate | - |
? | |
| tetrahydrofolate + N-formimidoyl-L-glutamate | FTCD in the centrosome may be associated with polyglutamylated residues of centriole microtubules and may play a role in providing centrioles with glutamate produced by cyclodeaminase domains of FTCD | Homo sapiens | 5-formimidoyltetrahydrofolate + L-glutamate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| formiminotransferase cyclodeaminase | - |
Homo sapiens |
| FTCD | - |
Homo sapiens |
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