Application | Comment | Organism |
---|---|---|
diagnostics | enzyme variants are used to predict methotrexate response in juvenile idiopathic arthritis, overview | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
gene ATIC, genotyping of single nucleotide polymorphisms | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P31939 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Synonyms | Comment | Organism |
---|---|---|
5-aminoimidazole-4-carboxamide ribonucleotide-transformylase | - |
Homo sapiens |
ATIC | - |
Homo sapiens |
Bifunctional purine biosynthesis protein | - |
Homo sapiens |
PurH | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | the ATIC rs2372536 GG enzyme genotype is associated with improved clinical remission in juvenile idiopathic arthritis during methotrexate therapy, only one of the ATIC single nucleotide polymorphisms show any trend toward methotrexate response in an independent cohort of North American juvenile idiopathic arthritis children | Homo sapiens |