Literature summary for 2.1.2.2 extracted from

Liu, X.; Ding, Z.; Liu, Y.; Zhang, J.; Liu, F.; Wang, X.; He, X.; Cui, G.; Wang, D.
Glycinamide ribonucleotide formyl transferase is frequently overexpressed in glioma and critically regulates the proliferation of glioma cells (2014), Pathol. Res. Pract., 210, 256-263.

Search for more literature for 2.1.2.2

Application

Application	Comment	Organism
diagnostics	GART expression is associated with glioma grade and high GART protein expression might be related to poor outcome	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	silencing of GART expression by RNA interference	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
lometrexol	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P22102	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	enzyme immunohistochemic analysis in 70 cases of human gliomas and normal brain tissues, overview	Homo sapiens	-
glioblastoma cell	-	Homo sapiens	-
glioma cell	the enzyme is frequently overexpressed in glioma, enzyme immunohistochemic analysis in 70 cases of human gliomas and normal brain tissues, overview	Homo sapiens	-
H-4 cell	-	Homo sapiens	-
U87-MG cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
GART	-	Homo sapiens
glycinamide ribonucleotide formyl transferase	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	transfecting cells with GART-siRNA suppresses proliferation and enhances temozolomide-induced apoptosis in glioma cells	Homo sapiens
physiological function	glycinamide ribonucleotide formyl transferase is frequently overexpressed in glioma and critically regulates the proliferation of glioma cells	Homo sapiens

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Release 2023.1 (January 2023)