Literature summary for 2.1.2.2 extracted from

Liu, C.; Shim, J.H.; Benkovic, S.J.
The unexpected catalytic properties of a heterodimer of GAR transformylase (2000), Bioorg. Chem., 28, 316-323.

Search for more literature for 2.1.2.2

Cloned(Commentary)

Cloned (Comment)	Organism
-	Escherichia coli

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0123	-	10-formyl-5,8-dideazafolate	wild-type	Escherichia coli
0.118	-	beta-glycinamide ribonucleotide	wild-type	Escherichia coli
0.128	-	10-formyl-5,8-dideazafolate	mutant 13N + 13C 1:1	Escherichia coli
0.131	-	10-formyl-5,8-dideazafolate	mutant B13	Escherichia coli
0.178	-	beta-glycinamide ribonucleotide	mutant B13	Escherichia coli
0.19	-	beta-glycinamide ribonucleotide	mutant 13N + 13C 1:1	Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
11200	-	1 * 12100 + 1 * 11200, heterodimer, SDS-PAGE	Escherichia coli
12100	-	1 * 12100 + 1 * 11200, heterodimer, SDS-PAGE	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	-	Escherichia coli	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?

Subunits

Subunits	Comment	Organism
dimer	1 * 12100 + 1 * 11200, heterodimer, SDS-PAGE	Escherichia coli

pH Range

pH Minimum	pH Maximum	Comment	Organism
6	9.5	-	Escherichia coli

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Release 2023.1 (January 2023)