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Literature summary for 2.1.2.11 extracted from

  • Villasenor, T.; Brom, S.; Davalos, A.; Lozano, L.; Romero, D.; Los Santos, A.G.
    Housekeeping genes essential for pantothenate biosynthesis are plasmid-encoded in Rhizobium etli and Rhizobium leguminosarum (2011), BMC Microbiol., 11, 66.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene panB, phylogenetic analysis, genes panBC in Rhizobiales with multipartite genomes, overview Rhizobium etli

Protein Variants

Protein Variants Comment Organism
additional information construction of several plasmid-encoded panB mutants, effects on pantothenate biosynthesis, growth inhibition of pan B mutants, overview Rhizobium etli

Organism

Organism UniProt Comment Textmining
Rhizobium etli
-
genomic gene panB, and a second putative MOHMT enzyme, RHE_PE00443, similar to the product of panB, is encoded on plasmid p42e
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Rhizobium etli CFN 42
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genomic gene panB, and a second putative MOHMT enzyme, RHE_PE00443, similar to the product of panB, is encoded on plasmid p42e
-

Synonyms

Synonyms Comment Organism
ketopantoate hydroxymethyltransferase
-
Rhizobium etli
KPHMT
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Rhizobium etli
MOHMT
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Rhizobium etli

General Information

General Information Comment Organism
evolution phylogenetic analysis of rhizobial panCB genes indicates a common origin of chromosomal and plasmid-borne sequences. Gene pan B in Rhizobiales with multipartite genomes, overview Rhizobium etli
metabolism the enzyme is the first enzyme of the pantothenate biosynthesis pathway, responsible for the formation of 2-oxopantoate by the transfer of a methyl group from 5,10-methylentetrahydrofolate to 2-oxoisovalerate Rhizobium etli
additional information the putative MOHMT encoded by RHE_PE00443 is not functional under the conditions studied and provides evidence of functional cooperation between p42f and chromosomally encoded proteins for pantothenate biosynthesis Rhizobium etli