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Literature summary for 2.1.1.B74 extracted from

  • Lee, H.; Kim, B.; Kim, M.; Ahn, J.
    Biosynthesis of two flavones, apigenin and genkwanin, in Escherichia coli (2015), J. Microbiol. Biotechnol., 25, 1442-1448.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
recombinant expression of tagged enzyme in Escherichia coli, coexpression with tyrosine ammonia lyase, 4-coumaroyl coenzyme A ligase, chalcone synthase, chalcone isomerase, flavone synthase, and apigenin 7-O-methyltransferase to resonstitute genkwanin production from tyrosine in transformed Escherichia coli, method, overview Populus deltoides

Protein Variants

Protein Variants Comment Organism
additional information coexpression of the apigenin 7-O-methyltransferase with tyrosine ammonia lyase, 4-coumaroyl coenzyme A ligase, chalcone synthase, chalcone isomerase,and flavone synthase to resonstitute genkwanin production from tyrosine in transformed Escherichia coli with modulated tyrosine content, method, overview Populus deltoides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + apigenin Populus deltoides
-
S-adenosyl-L-homocysteine + 7-O-methylapigenin i.e. genkwanin ?

Organism

Organism UniProt Comment Textmining
Populus deltoides
-
gene POMT-7
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + apigenin
-
Populus deltoides S-adenosyl-L-homocysteine + 7-O-methylapigenin i.e. genkwanin ?

Synonyms

Synonyms Comment Organism
flavonoid 7-O-methyltransferase
-
Populus deltoides
POMT-7
-
Populus deltoides
POMT7
-
Populus deltoides

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
Populus deltoides

General Information

General Information Comment Organism
metabolism the enzyme catalyzes the last step in genkwanin biosynthesis from tyrosine Populus deltoides