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Literature summary for 2.1.1.86 extracted from
- Tetrahydromethanopterin methyltransferase, a component of the methane synthesizing complex of Methanobacterium thermoautotrophicum (1986), Biochem. Biophys. Res. Commun., 136, 542-547.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.88 | - |
5,6,7,8-tetrahydromethanopterin | - |
Methanothermobacter thermautotrophicus |  |
| 3.7 | - |
(2-methylthio)ethanesulfonate | - |
Methanothermobacter thermautotrophicus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate | Methanothermobacter thermautotrophicus | involved in the formation of methane from CO | 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methanothermobacter thermautotrophicus | - |
- |
- |
Oxidation Stability
| Oxidation Stability | Organism |
|---|---|
| oxygen-sensitive | Methanothermobacter thermautotrophicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate | - |
Methanothermobacter thermautotrophicus | 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate | - |
r | |
| 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate | involved in the formation of methane from CO | Methanothermobacter thermautotrophicus | 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate | - |
r | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | - |
assay at | Methanothermobacter thermautotrophicus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 100 | - |
5 min, inactivation | Methanothermobacter thermautotrophicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.7 | - |
- |
Methanothermobacter thermautotrophicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 7 | sharp decrease in activity below pH 6.0 and above pH 7.0 | Methanothermobacter thermautotrophicus |
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Release 2023.1 (January 2023)
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