Activating Compound | Comment | Organism | Structure |
---|---|---|---|
5-Methylhistamine | 0.001-0.5 mM, activation | Sus scrofa | |
N',N'-dimethylhistamine | 0.001-0.5 mM, activation | Sus scrofa | |
Nalpha-methylhistamine | 0.001-0.5 mM, activation | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-Methylhistamine | strong | Sus scrofa | |
2-Methylhistamine | strong | Sus scrofa | |
3-Methylhistamine | strong | Sus scrofa | |
5-Methylhistamine | weak | Sus scrofa | |
Nalpha-methylhistamine | weak | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mucosa | antrum mucosa | Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + histamine | - |
Sus scrofa | S-adenosyl-L-homocysteine + Ntau-methylhistamine | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.3 | - |
N-methylhistamine | Sus scrofa |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 10.5 | about 50% of maximum activity at pH 6.5 and pH 10.5, N-methylhistamine | Sus scrofa |