Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.77 extracted from

  • Hicks, W.M.; Kotlajich, M.V.; Visick, J.E.
    Recovery from long-term stationary phase and stress survival in Escherichia coli require the L-isoaspartyl protein carboxyl methyltransferase at alkaline pH (2005), Microbiology, 151, 2151-2158.
    View publication on PubMed
Search for more literature for 2.1.1.77

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + protein L-isoaspartate Escherichia coli the enzyme can stimulate repair of isoaspartyl residues arising spontaneously in proteins to normal L-aspartyl residues. Protein repair by the enzyme plays a key role in long-term stress survival only at alkaline pH in Escherichia coli, and it may function primarily to repair damage in cells that are recovering from nutrient limitation and those cells that are able to divide during long-term stationary phase S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + protein L-isoaspartate the enzyme can stimulate repair of isoaspartyl residues arising spontaneously in proteins to normal L-aspartyl residues. Protein repair by the enzyme plays a key role in long-term stress survival only at alkaline pH in Escherichia coli, and it may function primarily to repair damage in cells that are recovering from nutrient limitation and those cells that are able to divide during long-term stationary phase Escherichia coli S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Synonyms

Synonyms Comment Organism
L-isoaspartyl protein carboxyl methyltransferase
-
 Escherichia coli
PCM
-
 Escherichia coli