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Literature summary for 2.1.1.74 extracted from
- Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria -evolutionary implications (2005), Nucleic Acids Res., 33, 3955-3964.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| the encoded recombinant protein contains tightly bound flavin and is active in Escherichia coli mutant lacking m5U-54 in tRNAs and in vitro using T7 tRNA transcript as substrate | Bacillus subtilis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | P39815 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2 | - |
Bacillus subtilis | tetrahydrofolate + tRNA TpsiC + FAD | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TRMFO | - |
Bacillus subtilis |
| tRNA:m5U-54 MTase | - |
Bacillus subtilis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | contains tightly bound flavin | Bacillus subtilis | |
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Release 2023.1 (January 2023)
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