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Literature summary for 2.1.1.72 extracted from
- Characterization of the NgoAXP: phase-variable type III restriction-modification system in Neisseria gonorrhoeae (2009), FEMS Microbiol. Lett., 300, 25-35.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli GM2163 cells | Neisseria gonorrhoeae |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 77500 | - |
calculated from amino acid sequence | Neisseria gonorrhoeae |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + DNA adenine | Neisseria gonorrhoeae | the specific sequence recognized by M.NgoAXP is 5'-CCACC-3', in which the adenine residue is methylated | S-adenosyl-L-homocysteine + DNA 6-methyladenine | - |
? |  |
| S-adenosyl-L-methionine + DNA adenine | Neisseria gonorrhoeae FA 1090 | the specific sequence recognized by M.NgoAXP is 5'-CCACC-3', in which the adenine residue is methylated | S-adenosyl-L-homocysteine + DNA 6-methyladenine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neisseria gonorrhoeae | - |
- |
- |
| Neisseria gonorrhoeae FA 1090 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA agarose column chromatography | Neisseria gonorrhoeae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + DNA adenine | the specific sequence recognized by M.NgoAXP is 5'-CCACC-3', in which the adenine residue is methylated | Neisseria gonorrhoeae | S-adenosyl-L-homocysteine + DNA 6-methyladenine | - |
? | |
| S-adenosyl-L-methionine + DNA adenine | the specific sequence recognized by M.NgoAXP is 5'-CCACC-3', in which the adenine residue is methylated | Neisseria gonorrhoeae FA 1090 | S-adenosyl-L-homocysteine + DNA 6-methyladenine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DNA methyltransferase | - |
Neisseria gonorrhoeae |
| M.NgoAXP | - |
Neisseria gonorrhoeae |
| NgoAXPMod subunit | - |
Neisseria gonorrhoeae |
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