Application | Comment | Organism |
---|---|---|
medicine | upregulation of recombinational repair in dam mutants allows for the efficient repair of double-strand breaks whose formation is dependent on functional mismatch repair | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
additional information | mutant strains dam, dam mutS, and mutS, deficient in dam and/or mismatch repair, mutS strain does not display many differences from the wild-type at the transcriptional level, both dam and dam mutS strains show differential expression of 206 and 114 genes and expression at higher levels as wild-type, dam mutS strain shows higher variability among some of these induced genes than the dam strain, dam strain has a significantly higher level of basal double-strand breaks than the dam mutS strain | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
derivatives of strain AB1157 | - |
Synonyms | Comment | Organism |
---|---|---|
Dam | - |
Escherichia coli |
DNA adenine methyltransferase | - |
Escherichia coli |