Any feedback?
Literature summary for 2.1.1.71 extracted from
- Phosphatidylethanolamine N-methyltransferase activity in isolated rod outer segments from bovine retina (1995), Exp. Eye Res., 60, 631-643.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.037 | - |
S-adenosyl-L-methionine | pH 8.5 | Bos taurus |  |
| 0.038 | - |
S-adenosyl-L-methionine | pH 10.0 | Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Bos taurus | 5829 | - |
| membrane | synaptosomal plasma membrane | Rattus norvegicus | 16020 | - |
| microsome | - |
Rattus norvegicus | - |
- |
| microsome | - |
Bos taurus | - |
- |
| mitochondrion | - |
Bos taurus | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | requires magnesium ions for full activity | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
bovine | - |
| Rattus norvegicus | - |
rat | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| eye | - |
Bos taurus | - |
| liver | - |
Rattus norvegicus | - |
| retina | rod outer segments | Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + phosphatidylcholine | - |
? | |
| S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine | - |
Bos taurus | S-adenosyl-L-homocysteine + phosphatidylcholine | - |
? | |
| S-adenosyl-L-methionine + phosphatidylethanolamine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + phosphatidyl-N-monomethylethanolamine | - |
? | |
| S-adenosyl-L-methionine + phosphatidylethanolamine | - |
Bos taurus | S-adenosyl-L-homocysteine + phosphatidyl-N-monomethylethanolamine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PE N-MTase | - |
Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
low substrate concentrations about 0.01 M S-adenosyl-L-methionine | Bos taurus |
| 10 | - |
- |
Rattus norvegicus |
| 10 | - |
high substrate concentrations about 0.2 M S-adenosyl-L-methionine | Bos taurus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 11 | - |
Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
