Application | Comment | Organism |
---|---|---|
medicine | inhibition of tumor suppressor p53 by RNAi is accompanied by down-regulation of MGMT gene expression, but is not associated with a discernible change in the pattern of MGMT promoter methylation | Homo sapiens |
medicine | tumor suppressor p53 positively regulates MGMT gene expression in murine astrocytes | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
newborn C57bl/6 mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | - |
Homo sapiens | - |
astrocyte | MGMT gene expression is substantially lower in knockout p53 astrocytes than in wild-type p53 astrocytes | Mus musculus | - |
cerebrum | - |
Mus musculus | - |
glioma cell line | - |
Homo sapiens | - |
SF-767 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
MGMT | - |
Mus musculus |
MGMT | - |
Homo sapiens |
O6-methylguanine-DNA methyltransferase | - |
Mus musculus |
O6-methylguanine-DNA methyltransferase | - |
Homo sapiens |