Application | Comment | Organism |
---|---|---|
medicine | high level of enzyme in tumors and relative resistance to cyclophosphamide in lung cancer indicates that 6-O-methylguanine-DNA methyltransferase may be a predictive factor of resistance to cyclophosphamide | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | high level of enzyme in tumors and relative resistance to cyclophosphamide in lung cancer indicates that 6-O-methylguanine-DNA methyltransferase may be a predictive factor of resistance to cyclophosphamide | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung cancer cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA containing 6-O-methylguanine + [protein]-L-cysteine | - |
Homo sapiens | DNA lacking 6-O-methylguanine + [protein]-S-methyl-L-cysteine | - |
? |