Any feedback?
Literature summary for 2.1.1.63 extracted from
- Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue (1980), J. Biol. Chem., 255, 10569-10571.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | transferase activity methylates itself on removal of the methyl group from the 6-O position of guanine. Modification of a reactive sulfhydryl group can account for the enzyme inactivation accompanying the reaction | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA containing 6-O-methylguanine + [protein]-L-cysteine | transferase activity methylates itself on removal of the methyl group from the 6-O position of guanine | Escherichia coli | DNA lacking 6-O-methylguanine + [protein]-S-methyl-L-cysteine | - |
? |  |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
