Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,5-dinitrocatechol | uncompetitive inhibitor | Sus scrofa domesticus | |
Cistus parviflorus leaf extract | mixed type inhibition | Sus scrofa domesticus | |
Harmaline | - |
Sus scrofa domesticus | |
harmalol | - |
Sus scrofa domesticus | |
Peganum harmala seed extract | mixed type inhibition | Sus scrofa domesticus | |
Vitex agnus-cactus leaf extract | mixed type inhibition | Sus scrofa domesticus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0035 | - |
S-adenosyl-L-methionine | pH 7.4, 37°C | Sus scrofa domesticus | |
0.0064 | - |
aesculetin | pH 7.4, 37°C | Sus scrofa domesticus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa domesticus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
commercial preparation | Sus scrofa domesticus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa domesticus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00107 | - |
pH 7.4, 37°C | Sus scrofa domesticus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
aesculetin + S-adenosyl-L-methionine | - |
Sus scrofa domesticus | scopoletin + S-adenosyl-L-homocysteine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
catechol-O-methyltransferase | - |
Sus scrofa domesticus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000456 | - |
3,5-dinitrocatechol | pH 7.4, 37°C | Sus scrofa domesticus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00004418 | - |
pH 7.4, 37°C | Sus scrofa domesticus | 3,5-dinitrocatechol | |
0.00457 | - |
pH 7.4, 37°C | Sus scrofa domesticus | Harmaline | |
0.01319 | - |
pH 7.4, 37°C | Sus scrofa domesticus | harmalol |