KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00501 | - |
S-adenosyl-L-methionine | membrane-bound activity | Rattus norvegicus | |
0.00863 | - |
S-adenosyl-L-methionine | soluble activity | Rattus norvegicus | |
0.009 | - |
epinephrine | membrane-bound activity | Rattus norvegicus | |
0.59 | 1 | epinephrine | soluble activity | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | bound to, MB-COMT | Rattus norvegicus | 16020 | - |
soluble | S-COMT | Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | Km: 0.21 mM for soluble activity, Km: 0.15 mM for membrane-bound activity | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | COMT in the adrenal gland might not be related to blood pressure regulation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | COMT in the adrenal gland might not be related to blood pressure regulation | Rattus norvegicus | ? | - |
? | |
S-adenosyl-L-methionine + epinephrine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + metanephrine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
COMT | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
membrane-bound activity | Rattus norvegicus |
7.8 | - |
soluble activity | Rattus norvegicus |