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Literature summary for 2.1.1.57 extracted from

  • Schnierle, B.S.; Gershon, P.; Moss, B.
    Cap-specific mRNA (nucleoside-O2-)-methyltransferase and poly(A) polymerase stimulatory activities of vaccinia virus are mediated by a single protein (1992), Proc. Natl. Acad. Sci. USA, 89, 2897-2901.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
viral nucleocapsid
-
Vaccinia virus 19013
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
gel filtration Vaccinia virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + m7G(5')pppR-RNA Vaccinia virus RNA-polymerase holoenzyme has methyltransferase activity: the same protein acts as methyltransferase and poly(A)-polymerase stimulatory factor VP39 S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?
S-adenosyl-L-methionine + m7G(5')pppR-RNA Vaccinia virus WR RNA-polymerase holoenzyme has methyltransferase activity: the same protein acts as methyltransferase and poly(A)-polymerase stimulatory factor VP39 S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?

Organism

Organism UniProt Comment Textmining
Vaccinia virus
-
-
-
Vaccinia virus WR
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Vaccinia virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + m7G(5')pppR-RNA brome mosaic virus RNA ending in m7G(5')pppG as substrate Vaccinia virus S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?
S-adenosyl-L-methionine + m7G(5')pppR-RNA RNA-polymerase holoenzyme has methyltransferase activity: the same protein acts as methyltransferase and poly(A)-polymerase stimulatory factor VP39 Vaccinia virus S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?
S-adenosyl-L-methionine + m7G(5')pppR-RNA brome mosaic virus RNA ending in m7G(5')pppG as substrate Vaccinia virus WR S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?
S-adenosyl-L-methionine + m7G(5')pppR-RNA RNA-polymerase holoenzyme has methyltransferase activity: the same protein acts as methyltransferase and poly(A)-polymerase stimulatory factor VP39 Vaccinia virus WR S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?