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Literature summary for 2.1.1.56 extracted from

  • Cross, R.K.
    Identification of a unique guanine-7-methyltransferase in Semliki Forest virus (SFV) infected cell extracts (1983), Virology, 130, 452-463.
    View publication on PubMed

General Stability

General Stability Organism
expression and enzyme activity stable for 3 h in infected BHK cells Semliki forest virus

Inhibitors

Inhibitors Comment Organism Structure
cycloheximide inhibits protein synthesis in infected BHK cells Semliki forest virus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion of infected BHK cells Semliki forest virus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + G(5')pppR-RNA Semliki forest virus in infected BHK cells S-adenosyl-L-homocysteine + m7G(5')pppR-RNA
-
?

Organism

Organism UniProt Comment Textmining
Semliki forest virus
-
in infected BHK cells
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + G(5')pppR-RNA
-
Semliki forest virus S-adenosyl-L-homocysteine + m7G(5')pppR-RNA R may be guanosine or adenosine, mRNA containing an N7-methylguanine cap ?
S-adenosyl-L-methionine + G(5')pppR-RNA in infected BHK cells Semliki forest virus S-adenosyl-L-homocysteine + m7G(5')pppR-RNA
-
?
S-adenosyl-L-methionine + GTP viral, not host enzyme Semliki forest virus S-adenosyl-L-homocysteine + m7GTP
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Semliki forest virus