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Literature summary for 2.1.1.53 extracted from

  • Zhang, L.; Ding, R.; Chai, Y.; Bonfill, M.; Moyano, E.; Oksman-Caldentey, K.M.; Xu, T.; Pi, Y.; Wang, Z.; Zhang, H.; Kai, G.; Liao, Z.; Sun, X.; Tang, K.
    Engineering tropane biosynthetic pathway in Hyoscyamus niger hairy root cultures (2004), Proc. Natl. Acad. Sci. USA, 101, 6786-6791.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
synthesis overexpression of enzyme is not sufficient to boost scopolamine biosynthesis. Simultaneous overexpression of enzyme and hyoscyamine 6 beta-hydroxylase results in sígnificant enhancement of scopolamine accumulation Hyoscyamus niger

Organism

Organism UniProt Comment Textmining
Hyoscyamus niger
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overexpression of enzyme, coexpression of hyoscyamine 6 beta-hydroxylase
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Source Tissue

Source Tissue Comment Organism Textmining
cell culture root culture Hyoscyamus niger
-