Cloned (Comment) | Organism |
---|---|
expression analysis by RT-PCR | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | during differentiation, Dnmt1 is retained in the cytoplasm in metaphase II stage oocytes and zygotes but enters the nuclei of 8-16 cell stage embryos | Bos taurus | 5737 | - |
nucleus | during differentiation, Dnmt1 is retained in the cytoplasm in metaphase II stage oocytes and zygotes but enters the nuclei of 8-16 cell stage embryos | Bos taurus | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + S-adenosyl-L-methionine | Bos taurus | - |
DNA containing 5-methylcytosine + S-adenosyl-L-homocysteine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | Q24K09 | female cows | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | immunohistochemic analysis | Bos taurus | - |
oocyte | during differentiation, Dnmt1 is retained in the cytoplasm in metaphase II stage oocytes and zygotes but enters the nuclei of 8-16 cell stage embryos | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + S-adenosyl-L-methionine | - |
Bos taurus | DNA containing 5-methylcytosine + S-adenosyl-L-homocysteine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DNA methyltransferase-1 | - |
Bos taurus |
Dnmt1 | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-methionine | - |
Bos taurus |
General Information | Comment | Organism |
---|---|---|
physiological function | Dnmt1 is involved in DNA methylation pattern regulation during the late stage oocyte differentiation, maturation and early embryonic development, overview | Bos taurus |