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Literature summary for 2.1.1.321 extracted from

  • Zurita-Lopez, C.; Sandberg, T.; Kelly, R.; Clarke, S.
    Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming omega-NG-monomethylated arginine residues (2012), J. Biol. Chem., 287, 7859-7870.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.321

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
78000
-
 x * 78000, calculated Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NVM4 isoform PRMT7
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3 S-adenosyl-L-methionine + SGRGKGGKGLGKGGAKRHRK-NH2
-
 Homo sapiens 3 S-adenosyl-L-homocysteine + SG-(Nomega-Me)RGKGGKGLGKGGAK-(Nomega-Me)RH-(Nomega-Me)RK-NH2
-
 ?
5 S-adenosyl-L-methionine + AGRGRGKAAILKAQVAARGRGRGMGRGN-NH2
-
 Homo sapiens 5 S-adenosyl-L-homocysteine + AG-(Nomega-Me)RG-(Nomega-Me)RGKAAILKAQVAA-(Nomega-Me)RG-(Nomega-Me)RGRGMG-(Nomega-Me)RGN-NH2
-
 ?
additional information enzyme is capable of forming only omega-NG-monomethylarginine, not asymmetric omega-NG,NG-dimethylarginine or symmetric omega-NG,NG-dimethylarginine. No substrates: SGAGKGGKGLGKGGAKAHAK-NH2, GRG-NH2 Homo sapiens ?
-
 ?
S-adenosyl-L-methionine + acetyl-GGRGG-NH2 substrate is a synthetic peptide Homo sapiens S-adenosyl-L-homocysteine + acetyl-GG-(Nomega-methyl-)RGG-NH2
-
 ?
S-adenosyl-L-methionine + GGFGGRGGFG-NH2 substrate is a synthetic peptide Homo sapiens S-adenosyl-L-homocysteine + GGFGG-(Nomega-methyl-)RGGFG-NH2 product is monomethylated at residue R6 ?
S-adenosyl-L-methionine + SG-(Nomega-methyl-)RGKGGKGLGKGGAKRHRK-NH2
-
 Homo sapiens S-adenosyl-L-homocysteine + SG-(Nomega-methyl-)RGKGGKGLGKGGAK-(Nomega-methyl-)RHRK-NH2
-
 ?
S-adenosyl-L-methionine + [GST-GAR]-L-arginine
-
 Homo sapiens S-adenosyl-L-homocysteine + [GST-GAR]-Nomega-methyl-L-arginine
-
 ?
S-adenosyl-L-methionine + [histone H2A]-L-arginine
-
 Homo sapiens S-adenosyl-L-homocysteine + [histone H2A]-Nomega-methyl-L-arginine
-
 ?
S-adenosyl-L-methionine + [histone H2B]-L-arginine
-
 Homo sapiens S-adenosyl-L-homocysteine + [histone H2B]-Nomega-methyl-L-arginine
-
 ?
S-adenosyl-L-methionine + [histone H3]-L-arginine
-
 Homo sapiens S-adenosyl-L-homocysteine + [histone H3]-Nomega-methyl-L-arginine
-
 ?
S-adenosyl-L-methionine + [myelin basic protein]-L-arginine
-
 Homo sapiens S-adenosyl-L-homocysteine + [myelin basic protein]-Nomega-methyl-L-arginine
-
 ?
S-adenosyl-L-methionine + [Smb protein]-L-arginine
-
 Homo sapiens S-adenosyl-L-homocysteine + [Smb protein]-Nomega-methyl-L-arginine
-
 ?

Subunits

Subunits Comment Organism
? x * 78000, calculated Homo sapiens