Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | P46580 | - |
- |
Homo sapiens | O14744 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 S-adenosyl-L-methionine + [D2 dopamine receptor]-L-arginine | recombinant fragment of the third intracellular loop of D2, corresponding to amino acid residues 211 to 241 fused to glutathione S-transferase. Residues Arg217 and Arg219 are key methylation sites within this region | Homo sapiens | 2 S-adenosyl-L-homocysteine + [D2 dopamine receptor]-Nomega,Nomega'-dimethyl-L-arginine | - |
? | |
2 S-adenosyl-L-methionine + [DOP-3 receptor]-L-arginine | recombinant fragment of the third intracellular loop of Caenorhabditis elegans DOP-3, amino acid residues 202 to 232 fused to GST. Residues Arg208 and Arg210 are key methylation sites within this region | Homo sapiens | 2 S-adenosyl-L-homocysteine + [DOP-3 receptor]-Nomega,Nomega'-dimethyl-L-arginine | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | Caenorhabditis elegans lacking PRMT-5 are hypersensitive to dilute octanol. PRMT-5 contributes to the regulation of locomotion by both exogenous and endogenous dopamine | Caenorhabditis elegans |