Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | predominant localization | Homo sapiens | 5737 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
68000 | - |
sedimentation analysis | Homo sapiens |
72000 | - |
1 * 72000, SDS-PAGE | Homo sapiens |
72000 | - |
2 * 72000, SDS-PAGE | Homo sapiens |
72000 | - |
4 * 72000, SDS-PAGE | Homo sapiens |
158000 | - |
sedimentation analysis | Homo sapiens |
240000 | - |
sedimentation analysis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O14744 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293T cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | myelin basic protein methylated by PRMT5 contains monomethylated and dimethylated arginine residues | Homo sapiens | ? | - |
? | |
S-adenosyl-L-methionine + [GST-fibrillarin]-L-arginine | substrate is amino terminus of fibrillarin fused to glutathione S-transferase | Homo sapiens | S-adenosyl-L-homocysteine + [GST-fibrillarin]-Nomega-methyl-L-arginine | - |
? | |
S-adenosyl-L-methionine + [GST-fibrillarin]-Nomega-methyl-L-arginine | - |
Homo sapiens | S-adenosyl-L-homocysteine + [GST-fibrillarin]-Nomega,Nomega'-dimethyl-L-arginine | - |
? | |
S-adenosyl-L-methionine + [histone]-L-arginine | - |
Homo sapiens | S-adenosyl-L-homocysteine + [histone]-Nomega-methyl-L-arginine | - |
? | |
S-adenosyl-L-methionine + [histone]-Nomega-methyl-L-arginine | - |
Homo sapiens | S-adenosyl-L-homocysteine + [histone]-Nomega,Nomega'-dimethyl-L-arginine | - |
? | |
S-adenosyl-L-methionine + [myelin basic protein]-L-arginine | - |
Homo sapiens | S-adenosyl-L-homocysteine + [myelin basic protein]-Nomega-methyl-L-arginine | - |
? | |
S-adenosyl-L-methionine + [myelin basic protein]-Nomega-methyl-L-arginine | - |
Homo sapiens | S-adenosyl-L-homocysteine + [myelin basic protein]-Nomega,Nomega'-dimethyl-L-arginine | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 72000, SDS-PAGE | Homo sapiens |
monomer | 1 * 72000, SDS-PAGE | Homo sapiens |
More | PRMT5 forms distinct homooligomeric complexes, including a dimer and tetramer. The PRMT5 homo-oligomers are dissociated into a monomer in the presence of a reducing agent, whereas a monomer, dimer, and multimer are detected in the absence or at low concentrations of a reducing agent | Homo sapiens |
tetramer | 4 * 72000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
Skb1 | - |
Homo sapiens |