Any feedback?
Literature summary for 2.1.1.258 extracted from
- A conformational change in the methyltransferase from Clostridium thermoaceticum facilitates the methyl transfer from (6S)-methyltetrahydrofolate to the corrinoid/iron-sulfur protein in the acetyl-CoA pathway (1996), Biochemistry, 35, 2476-2481.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4,4'-bis(1-(phenylamino)-8-naphthalenesulfonate) | - |
Moorella thermoacetica |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Moorella thermoacetica | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Moorella thermoacetica |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | only the protonated enzyme form is active | Moorella thermoacetica | ? | - |
? | |
| [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate | - |
Moorella thermoacetica | [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase | - |
Moorella thermoacetica |
| MeTr | - |
Moorella thermoacetica |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| Cobalamin | dependent on | Moorella thermoacetica | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.026 | - |
4,4'-bis(1-(phenylamino)-8-naphthalenesulfonate) | at pH 5.8 and 25°C | Moorella thermoacetica | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
