Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tetrahydrofolate | competitive inhibitor | Moorella thermoacetica | |
[methyl-Co(III) corrinoid Fe-S protein] | competitive inhibitor | Moorella thermoacetica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
5-methyltetrahydrofolate | in 50 mM MES, pH 5.1, at 25°C | Moorella thermoacetica | |
0.012 | - |
[Co(I) corrinoid Fe-S protein] | in 50 mM MES, pH 5.1, at 25°C | Moorella thermoacetica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Moorella thermoacetica | - |
formerly Clostridium thermoaceticum | - |
Purification (Comment) | Organism |
---|---|
- |
Moorella thermoacetica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate | - |
Moorella thermoacetica | [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase | - |
Moorella thermoacetica |
MeTr | - |
Moorella thermoacetica |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
14.7 | - |
5-methyltetrahydrofolate | in 50 mM MES, pH 5.1, at 25°C | Moorella thermoacetica | |
14.7 | - |
[Co(I) corrinoid Fe-S protein] | in 50 mM MES, pH 5.1, at 25°C | Moorella thermoacetica |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme performs a key step in the Wood-Ljungdahl pathway of acetyl-CoA synthesis | Moorella thermoacetica |