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Literature summary for 2.1.1.25 extracted from

  • Axelrod, J.; Daly, J.
    Phenol-O-methyltransferase (1968), Biochim. Biophys. Acta, 159, 472-478.
    View publication on PubMed
Search for more literature for 2.1.1.25

Inhibitors

Inhibitors Comment Organism Structure
Mg2+ 10 mM, 61% inhibition Cavia porcellus
NEM 0.1 mM, 90% inhibition Cavia porcellus
PCMB 0.01 mM, 85% inhibition Cavia porcellus
SKF 525 0.5 mM, 56% inhibition Cavia porcellus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Cavia porcellus
-
-

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Mus musculus
-
-
-
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland low activity Cavia porcellus
-
gut low activity Cavia porcellus
-
kidney
-
 Cavia porcellus
-
liver
-
 Cavia porcellus
-
liver
-
 Oryctolagus cuniculus
-
lung
-
 Cavia porcellus
-
spleen low activity Cavia porcellus
-
testis low activity Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + m-bromophenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + m-bromoanisole
-
 ?
S-adenosyl-L-methionine + m-chlorophenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + m-chloroanisole
-
 ?
S-adenosyl-L-methionine + m-methoxyphenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + 1,3-dimethoxybenzene
-
 ?
S-adenosyl-L-methionine + m-nitrophenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + m-nitroanisole
-
 ?
S-adenosyl-L-methionine + o-chlorophenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + o-chloroanisole
-
 ?
S-adenosyl-L-methionine + o-methoxyphenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + veratrole
-
 ?
S-adenosyl-L-methionine + o-methylphenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + o-methylanisole
-
 ?
S-adenosyl-L-methionine + p-chlorophenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + p-chloroanisole
-
 ?
S-adenosyl-L-methionine + p-ethylphenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + p-ethylanisole
-
 ?
S-adenosyl-L-methionine + p-hydroxyacetanilide
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + p-methoxyacetanilide
-
 ?
S-adenosyl-L-methionine + p-methoxyphenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + 1,4-dimethoxybenzene
-
 ?
S-adenosyl-L-methionine + p-methylphenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + p-methylanisole
-
 ?
S-adenosyl-L-methionine + phenol
-
 Cavia porcellus S-adenosyl-L-homocysteine + anisole
-
 ?
S-adenosyl-L-methionine + phenol
-
 Mus musculus S-adenosyl-L-homocysteine + anisole
-
 ?
S-adenosyl-L-methionine + phenol
-
 Oryctolagus cuniculus S-adenosyl-L-homocysteine + anisole
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6 8.3
-
 Cavia porcellus