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Literature summary for 2.1.1.245 extracted from

  • Grahame, D.; DeMoll, E.
    Partial reactions catalyzed by protein components of the acetyl-CoA decarbonylase synthase enzyme complex from Methanosarcina barkeri (1996), J. Biol. Chem., 271, 8352-8358.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin Methanosarcina barkeri the reaction is performed by the intact gamma subunit and fragments of the delta subunit, components of the proteolyzed acetyl-CoA decarbonylase synthase, ACDS, complex, overview a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin
-
r

Organism

Organism UniProt Comment Textmining
Methanosarcina barkeri
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin the reaction is performed by the intact gamma subunit and fragments of the delta subunit, components of the proteolyzed acetyl-CoA decarbonylase synthase, ACDS, complex, overview Methanosarcina barkeri a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin
-
r
a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin structures of tetrahydrosarcinapterin and N5-methyl-tetrahydrosarcinapterin, overview. The reaction is performed by the intact gamma subunit and fragments of the delta subunit, components of the proteolyzed acetyl-CoA decarbonylase synthase, ACDS, complex, overview Methanosarcina barkeri a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin
-
r
CH3-H4SPt + cob(I)amide-protein + H+
-
Methanosarcina barkeri H4SPt + CH3-cob(III)amide-protein
-
r

Synonyms

Synonyms Comment Organism
CH3-H4pteridine:cob(I)amide-protein methyltransferase
-
Methanosarcina barkeri

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
assay at Methanosarcina barkeri

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Methanosarcina barkeri

General Information

General Information Comment Organism
additional information loss of acetyl-CoA synthesis activity of the beta-subunit of the enzyme complex does not influence the gamma and delta subunit activities Methanosarcina barkeri