Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.244 extracted from

  • Webb, K.; Laganowsky, A.; Whitelegge, J.; Clarke, S.
    Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab (2008), J. Biol. Chem., 283, 35561-35568.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + Rpl12ab Saccharomyces cerevisiae the yeast Rpl12ab protein is dimethylated at the N-terminal proline residue, trimethylated at Lys-3 by Rkm2, and monomethylated at Arg66 S-adenosyl-L-homocysteine + ?
-
?
S-adenosyl-L-methionine + Rpl12ab Saccharomyces cerevisiae BY4742 the yeast Rpl12ab protein is dimethylated at the N-terminal proline residue, trimethylated at Lys-3 by Rkm2, and monomethylated at Arg66 S-adenosyl-L-homocysteine + ?
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae BY4742
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + Rpl12ab the yeast Rpl12ab protein is dimethylated at the N-terminal proline residue, trimethylated at Lys-3 by Rkm2, and monomethylated at Arg66 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + ?
-
?
S-adenosyl-L-methionine + Rpl12ab the yeast Rpl12ab protein is dimethylated at the N-terminal proline residue, trimethylated at Lys-3 by Rkm2, and monomethylated at Arg66. Utilization of top down mass spectrometry to determine the sites of methylation of Rpl12ab Saccharomyces cerevisiae S-adenosyl-L-homocysteine + ?
-
?
S-adenosyl-L-methionine + Rpl12ab the yeast Rpl12ab protein is dimethylated at the N-terminal proline residue, trimethylated at Lys-3 by Rkm2, and monomethylated at Arg66 Saccharomyces cerevisiae BY4742 S-adenosyl-L-homocysteine + ?
-
?
S-adenosyl-L-methionine + Rpl12ab the yeast Rpl12ab protein is dimethylated at the N-terminal proline residue, trimethylated at Lys-3 by Rkm2, and monomethylated at Arg66. Utilization of top down mass spectrometry to determine the sites of methylation of Rpl12ab Saccharomyces cerevisiae BY4742 S-adenosyl-L-homocysteine + ?
-
?

Synonyms

Synonyms Comment Organism
Rkm2
-
Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
Saccharomyces cerevisiae

General Information

General Information Comment Organism
evolution Rkm2 belongs to the SET domain methyltransferases Saccharomyces cerevisiae