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Literature summary for 2.1.1.204 extracted from

  • Rai, K.; Chidester, S.; Zavala, C.V.; Manos, E.J.; James, S.R.; Karpf, A.R.; Jones, D.A.; Cairns, B.R.
    Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish (2007), Genes Dev., 21, 261-266.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.204

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Danio rerio 5737
-

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Danio rerio
-

General Information

General Information Comment Organism
malfunction knockdown of Dnmt2 protein in zebrafish embryos confers differentiation defects in particular organs, including the retina, liver, and brain Danio rerio
physiological function Dnmt2 methylates an RNA species of about 80 bases, consistent with tRNA methylation. Thus, Dnmt2 promotes zebrafish development, likely through cytoplasmic RNA methylation Danio rerio