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Literature summary for 2.1.1.202 extracted from
- Cysteine of sequence motif VI is essential for nucleophilic catalysis by yeast tRNA m5C methyltransferase (2007), RNA, 13, 967-973.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C310A | the mutant shows only a slightly lower affinity for RNA compared to wild-type Trm4p. The C310A mutant of Trm4p is unable to bind RNA covalently as well as to transfer the methyl group from SAM to the RNA substrate since no activity was detectable | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Cys310 of motif VI is likely the nucleophilic catalyst of Trm4p | Saccharomyces cerevisiae | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Trm4p | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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