Literature summary for 2.1.1.20 extracted from

Luka, Z.; Ham, A.J.; Norris, J.L.; Yeo, E.J.; Yermalitsky, V.; Glenn, B.; Caprioli, R.M.; Liebler, D.C.; Wagner, C.
Identification of phosphorylation sites in glycine N-methyltransferase from rat liver (2006), Protein Sci., 15, 785-794.

Search for more literature for 2.1.1.20

Activating Compound

Activating Compound	Comment	Organism	Structure
glucagon	elevates GNMT activity	Rattus norvegicus

Application

Application	Comment	Organism
additional information	phosphorylated serine residues 71, 182, and 241, in GNMT prepared from liver tissue and hepatocytes an S9 additional residue is phosphorylated, in hepatocytes and in recombinant GNMT S139 is detected, serine 9 is also identified as a target for cAMP-dependent protein kinase in vitro, positions of these phosphorylated residues in the tertiary structure of GNMT indicate their possible effect on enzyme conformation and activity	Rattus norvegicus

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
32420	79000	mass spectrometry, mass spectra of the proteins greatly depend on the method of sample preparation and storage	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
from liver by anion and cation exchange chromatography and from isolated hepatocytes and liver tissue by immunoprecipitation	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
hepatocyte	-	Rattus norvegicus	-
liver	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
GNMT	-	Rattus norvegicus

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Release 2023.1 (January 2023)