Cloned (Comment) | Organism |
---|---|
introduction of tlrB into Streptomyces lividans confers tylosin resistance | Streptomyces fradiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + guanine748 in 23S rRNA | Streptomyces fradiae | in vivo TlrB modifies nucleotide G748 within helix 35 of 23S rRNA | S-adenosyl-L-homocysteine + N1-methyluanine748 in 23S rRNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces fradiae | Q9S1M6 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces fradiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + guanine748 in 23S rRNA | purified recombinant TlrB modifies G748 in 23S rRNA as well as in a 74 nucleotide RNA containing helix 35 and surrounding structures | Streptomyces fradiae | S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA | - |
? | |
S-adenosyl-L-methionine + guanine748 in 23S rRNA | in vivo TlrB modifies nucleotide G748 within helix 35 of 23S rRNA | Streptomyces fradiae | S-adenosyl-L-homocysteine + N1-methyluanine748 in 23S rRNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TlrB | - |
Streptomyces fradiae |