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Literature summary for 2.1.1.180 extracted from

  • Zelinskaya, N.; Witek, M.A.; Conn, G.L.
    The pathogen-derived aminoglycoside resistance 16S rRNA methyltransferase NpmA possesses dual m1A1408/m1G1408 specificity (2015), Antimicrob. Agents Chemother., 59, 7862-7865.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + adenine1408 in 16S rRNA Escherichia coli
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S-adenosyl-L-homocysteine + N1-methyladenine1408 in 16S rRNA
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli A8C927
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme possesses also methylates 30S subunits with guanine1408 Escherichia coli ?
-
?
S-adenosyl-L-methionine + adenine1408 in 16S rRNA
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Escherichia coli S-adenosyl-L-homocysteine + N1-methyladenine1408 in 16S rRNA
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?

Synonyms

Synonyms Comment Organism
NpmA
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Escherichia coli